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Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K(+) channel function

Studies of stress effects on the brain have traditionally focused on neurons, without considering the cerebral microcirculation. Here we report that stress impairs neurovascular coupling (NVC), the process that matches neuronal activity with increased local blood flow. A stressed phenotype was induc...

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Bibliografiset tiedot
Päätekijät: Longden, Thomas A., Dabertrand, Fabrice, Hill-Eubanks, David C., Hammack, Sayamwong E., Nelson, Mark T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034203/
https://ncbi.nlm.nih.gov/pubmed/24808139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401811111
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