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APE1 incision activity at abasic sites in tandem repeat sequences
Repetitive DNA sequences, such as are present in micro- and mini-satellites, telomeres, and trinucleotide repeats (linked to fragile X syndrome, Huntington disease, etc.), account for nearly 30% of the human genome. These domains exhibit enhanced susceptibility to oxidative attack to yield base modi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034141/ https://ncbi.nlm.nih.gov/pubmed/24703901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.03.014 |
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