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Nitric Oxide-Dependent Mitochondrial Biogenesis Generates Ca(2+) Signaling Profile of Lupus T Cells

Abnormal T cell activation and cell death underlie the pathology of systemic lupus erythematosus. Although mitochondrial hyperpolarization (MHP) represents an early and reversible checkpoint of T cell activation and apoptosis, lupus T cells exhibit persistent MHP. NO has recently been recognized as...

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Détails bibliographiques
Auteurs principaux: Nagy, Gyorgy, Barcza, Maureen, Gonchoroff, Nick, Phillips, Paul E., Perl, Andras
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034140/
https://ncbi.nlm.nih.gov/pubmed/15356113
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