Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants

About 80% of functional genes in the human genome are expressed in the brain and over 1,200 different genes have been associated with the pathogenesis of CNS disorders and dementia. Pharmacogenetic studies of psychotropic drug response have focused on determining the relationship between variations...

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Autores principales: Cacabelos, Ramón, Fernández-Novoa, Lucía, Martínez-Bouza, Rocío, McKay, Adam, Carril, Juan C., Lombardi, Valter, Corzo, Lola, Carrera, Iván, Tellado, Iván, Nebril, Laura, Alcaraz, Margarita, Rodríguez, Susana, Casas, Ángela, Couceiro, Verónica, Álvarez, Antón
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034082/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3103040
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