Brain-Derived Neurotrophic Factor in Human Subjects with Function-Altering Melanocortin-4 Receptor Variants

BACKGROUND: In rodents, hypothalamic brain-derived neurotrophic factor (BDNF) expression appears to be regulated by melanocortin-4 receptor (MC4R) activity. The impact of MC4R genetic variation on circulating BDNF in humans is unknown. OBJECTIVE: To compare BDNF concentrations of subjects with loss-...

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Главные авторы: Hohenadel, Maximilian G., Thearle, Marie S., Grice, Brian A., Huang, Hui, Dai, Meng-Hong, Tao, Ya-Xiong, Hunter, Lindsay A., Palaguachi, Gladys I., Mou, Zongyang, Kim, Rachel C., Tsang, Matthew M., Haack, Karin, Voruganti, V. Saroja, Cole, Shelley A., Butte, Nancy F., Comuzzie, Anthony G., Muller, Yunhua L., Baier, Leslie J., Krakoff, Jonathan, Knowler, William C., Yanovski, Jack A., Han, Joan C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033711/
https://ncbi.nlm.nih.gov/pubmed/24276017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2013.221
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