Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

Bipolar disorder and schizophrenia are two often severe disorders with high heritabilities. Recent studies have demonstrated a large overlap of genetic risk loci between these disorders but diagnostic and molecular distinctions still remain. Here, we perform a combined GWAS of 19,779 BP and SCZ case...

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Hauptverfasser: Ruderfer, Douglas M., Fanous, Ayman H., Ripke, Stephan, McQuillin, Andrew, Amdur, Richard L., Gejman, Pablo V., O’Donovan, Michael C., Andreassen, Ole A., Djurovic, Srdjan, Hultman, Christina M., Kelsoe, John R., Jamain, Stephane, Landén, Mikael, Leboyer, Marion, Nimgaonkar, Vishwajit, Nurnberger, John, Smoller, Jordan W., Craddock, Nick, Corvin, Aiden, Sullivan, Patrick F., Holmans, Peter, Sklar, Pamela, Kendler, Kenneth S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033708/
https://ncbi.nlm.nih.gov/pubmed/24280982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.138
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