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Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer
Tumor evolution presents a formidable obstacle that currently prevents the development of truly curative treatments for cancer. In this perspective, we advocate for the hypothesis that tumor cells with significantly elevated genomic content (polyploid tumor cells) facilitate rapid tumor evolution an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033620/ https://ncbi.nlm.nih.gov/pubmed/24904834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00123 |
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