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Quality by design approach for viral clearance by protein a chromatography
Protein A chromatography is widely used as a capture step in monoclonal antibody (mAb) purification processes. Antibodies and Fc fusion proteins can be efficiently purified from the majority of other complex components in harvested cell culture fluid (HCCF). Protein A chromatography is also capable...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033531/ https://ncbi.nlm.nih.gov/pubmed/23860745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24999 |
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