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Quality by design approach for viral clearance by protein a chromatography

Protein A chromatography is widely used as a capture step in monoclonal antibody (mAb) purification processes. Antibodies and Fc fusion proteins can be efficiently purified from the majority of other complex components in harvested cell culture fluid (HCCF). Protein A chromatography is also capable...

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Detalhes bibliográficos
Main Authors: Zhang, Min, Miesegaes, George R, Lee, Michael, Coleman, Daniel, Yang, Bin, Trexler-Schmidt, Melody, Norling, Lenore, Lester, Philip, Brorson, Kurt A, Chen, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033531/
https://ncbi.nlm.nih.gov/pubmed/23860745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24999
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