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Design of Glucagon-Like Peptide-1 Receptor Agonist for Diabetes Mellitus from Traditional Chinese Medicine

Glucagon-like peptide-1 (GLP-1) is a promising target for diabetes mellitus (DM) therapy and reduces the occurrence of diabetes due to obesity. However, GLP-1 will be hydrolyzed soon by the enzyme dipeptidyl peptidase-4 (DPP-4). We tried to design small molecular drugs for GLP-1 receptor agonist fro...

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Detalhes bibliográficos
Main Authors: Tang, Hsin-Chieh, Chen, Calvin Yu-Chian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033432/
https://ncbi.nlm.nih.gov/pubmed/24891870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/385120
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