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Proteolytic enzymes in embryonated chicken eggs sustain the replication of egg-grown low-pathogenicity avian influenza viruses in cells in the absence of exogenous proteases

Low pathogenic influenza viruses grow readily in embryonated chicken eggs but require the addition of exogenous proteases to grow in MDCK cell culture. In this study, we found that influenza viruses propagated previously in eggs, can grow for up to two passages in cell culture without the addition o...

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Detalhes bibliográficos
Main Authors: Kandeil, Ahmed, Bagato, Ola, Zaraket, Hassan, Debeauchamp, Jennifer, Krauss, Scott, El-Shesheny, Rabeh, Webby, Richard J., Ali, Mohamed A., Kayali, Ghazi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033294/
https://ncbi.nlm.nih.gov/pubmed/24626064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2014.02.023
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