Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor

OBJECTIVES: Apremilast, an oral phosphodiesterase 4 inhibitor, regulates inflammatory mediators. Psoriatic Arthritis Long-term Assessment of Clinical Efficacy 1 (PALACE 1) compared apremilast with placebo in patients with active psoriatic arthritis despite prior traditional disease-modifying antirhe...

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Autores principales: Kavanaugh, Arthur, Mease, Philip J, Gomez-Reino, Juan J, Adebajo, Adewale O, Wollenhaupt, Jürgen, Gladman, Dafna D, Lespessailles, Eric, Hall, Stephen, Hochfeld, Marla, Hu, ChiaChi, Hough, Douglas, Stevens, Randall M, Schett, Georg
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2014
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033106/
https://ncbi.nlm.nih.gov/pubmed/24595547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-205056
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