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Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment

The immune system has a key role to play in controlling cancer initiation and progression. T cell activation, which is central to anti-tumor immune responses, coincides with changes in cellular metabolism. Naïve T cells predominantly require an ATP generating metabolic profile, whereas proliferating...

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Detalhes bibliográficos
Main Authors: Mockler, Mary B., Conroy, Melissa J., Lysaght, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032940/
https://ncbi.nlm.nih.gov/pubmed/24904823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00107
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