Single-cell genomics for dissection of complex malaria infections

Most malaria infections contain complex mixtures of distinct parasite lineages. These multiple-genotype infections (MGIs) impact virulence evolution, drug resistance, intra-host dynamics, and recombination, but are poorly understood. To address this we have developed a single-cell genomics approach...

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Autori principali: Nair, Shalini, Nkhoma, Standwell C., Serre, David, Zimmerman, Peter A., Gorena, Karla, Daniel, Benjamin J., Nosten, François, Anderson, Timothy J.C., Cheeseman, Ian H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032849/
https://ncbi.nlm.nih.gov/pubmed/24812326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.168286.113
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