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Hydrophobic Variations of N-Oxide Amphiphiles for Membrane Protein Manipulation: Importance of Non-hydrocarbon Groups in the Hydrophobic Portion

This study introduces several N-oxide amphiphiles evaluated for a large membrane protein assembly. Among these N-oxide amphiphiles, cholate-based agents (CAO and CAO-1) displayed the most favorable behaviors for membrane protein stabilization. This result raises the possibility that the identity and...

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Detalhes bibliográficos
Main Authors: Chae, Pil Seok, Aiman, Sadaf, Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032789/
https://ncbi.nlm.nih.gov/pubmed/24347070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.201301097
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