Assessment of Acute Oral and Dermal Toxicity of 2 Ethyl-Carbamates with Activity against Rhipicephalus microplus in Rats

The acute oral and dermal toxicity of two new ethyl-carbamates (ethyl-4-bromophenyl-carbamate and ethyl-4-chlorophenyl-carbamate) with ixodicide activity was determined in rats. The oral LD(50) of each carbamate was 300 to 2000 mg/kg, and the dermal LD(50) of each carbamate was >5000 mg/kg. Clini...

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Bibliographic Details
Main Authors: Prado-Ochoa, María Guadalupe, Gutiérrez-Amezquita, Ricardo Alfonso, Abrego-Reyes, Víctor Hugo, Velázquez-Sánchez, Ana María, Muñoz-Guzmán, Marco Antonio, Ramírez-Noguera, Patricia, Angeles, Enrique, Alba-Hurtado, Fernando
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032735/
https://ncbi.nlm.nih.gov/pubmed/24883331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/956456
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