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The NMR Structures of (rGCUGAGGCU)(2) and (rGCGGAUGCU)(2): Probing the Structural Features that Shape the Thermodynamic Stability of GA Pairs

The NMR structures of [Formula: see text] and [Formula: see text] are reported. The internal loop, [Formula: see text] , is about 2 kcal/mol more stable than [Formula: see text] at 37 °C. The duplexes assemble into similar global folds characterized by the formation of tandem sheared GA pairs. The d...

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Bibliografiske detaljer
Main Authors: Tolbert, Blanton S., Kennedy, Scott D., Schroeder, Susan J., Krugh, Thomas R., Turner, Douglas H.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032317/
https://ncbi.nlm.nih.gov/pubmed/17279616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061350m
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