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NK1 Receptor Blockade Is Ineffective in Improving Outcome following a Balloon Compression Model of Spinal Cord Injury

The neuropeptide substance P (SP) is a well-known mediator of neurogenic inflammation following a variety of CNS disorders. Indeed, inhibition of SP through antagonism of its receptor, the tachykinin NK1 receptor, has been shown to be beneficial following both traumatic brain injury and stroke. Such...

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Autors principals: Leonard, Anna Victoria, Thornton, Emma, Vink, Robert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032275/
https://ncbi.nlm.nih.gov/pubmed/24859234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098364
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