Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer

We report here that polyethylene glycol (PEG) linked to near infrared dyes conjugated to chimeric mouse-human anti-carcinoembryonic antigen (CEA) antibody greatly improves imaging of liver metastases in a nude mouse model of colon-cancer experimental metastases. PEGylated and non-PEGylated DyLight 6...

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Bibliographic Details
Main Authors: Maawy, Ali A., Hiroshima, Yukihiko, Zhang, Yong, Luiken, George A., Hoffman, Robert M., Bouvet, Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032229/
https://ncbi.nlm.nih.gov/pubmed/24859320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097965
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