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Identification of a Therapeutic Dose of Continuously Delivered Erythropoietin in the Eye Using An Inducible Promoter System

Erythropoietin (EPO) can protect the retina from acute damage, but long-term systemic treatment induces polycythemia. Intraocular gene delivery of EPO is not protective despite producing high levels of EPO likely due to its bell-shaped dose curve. The goal of this study was to identify a therapeutic...

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Detalhes bibliográficos
Main Authors: Hines–Beard, Jessica, Desai, Siddharth, Haag, Rachel, Esumi, Noriko, D’Surney, Lauren, Parker, Scott, Richardson, Cody, Rex, Tonia S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032115/
https://ncbi.nlm.nih.gov/pubmed/23773177
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