A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).

Phosphoramide mustard-induced DNA interstrand cross-links were studied both in vitro and by computer simulation. The local determinants for the formation of phosphoramide mustard-induced DNA interstrand cross-links were defined by using different pairs of synthetic oligonucleotide duplexes, each of...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Dong, Q, Barsky, D, Colvin, M E, Melius, C F, Ludeman, S M, Moravek, J F, Colvin, O M, Bigner, D D, Modrich, P, Friedman, H S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12170
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