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Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia.

The ALLI gene, located at chromosome band 11q23, is involved in acute leukemia through a series of chromosome translocations and fusion to a variety of genes, most frequently to A4 and AF9. The fused genes encode chimeric proteins proteins. Because the Drosophila homologue of ALL1, trithorax, is a p...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Prasad, R, Yano, T, Sorio, C, Nakamura, T, Rallapalli, R, Gu, Y, Leshkowitz, D, Croce, C M, Canaani, E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618864/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12160
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