Mortalin/GRP75 Binds to Complement C9 and Plays a Role in Resistance to Complement-dependent Cytotoxicity

Mortalin/GRP75, the mitochondrial heat shock protein 70, plays a role in cell protection from complement-dependent cytotoxicity (CDC). As shown here, interference with mortalin synthesis enhances sensitivity of K562 erythroleukemia cells to CDC, whereas overexpression of mortalin leads to their resi...

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Main Authors: Saar Ray, Moran, Moskovich, Oren, Iosefson, Ohad, Fishelson, Zvi
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031552/
https://ncbi.nlm.nih.gov/pubmed/24719326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552406
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