Differences in UGT1A1, UGT1A7, and UGT1A9 Polymorphisms between Uzbek and Japanese Populations

BACKGROUND AND OBJECTIVES: Uridine-diphosphate glucuronosyltransferase 1A (UGT1A) is a key enzyme involved in irinotecan metabolism, and polymorphisms in the UGT1A gene are associated with irinotecan-induced toxicity. The aim of this study was to elucidate the allele frequencies of UGT1A polymorphis...

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Bibliographic Details
Main Authors: Maeda, Hiromichi, Hazama, Shoichi, Shavkat, Abdiev, Okamoto, Ken, Oba, Koji, Sakamoto, Junichi, Takahashi, Kenichi, Oka, Masaki, Nakamura, Daisuke, Tsunedomi, Ryouichi, Okayama, Naoko, Mishima, Hideyuki, Kobayashi, Michiya
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2014
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Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031424/
https://ncbi.nlm.nih.gov/pubmed/24453052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-014-0083-6
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