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Formulation and Characterization of Nanoemulsion Intranasal Adjuvants: Effects of Surfactant Composition on Mucoadhesion and Immunogenicity

Development of effective intranasal vaccines is of great interest due to their potential to induce both mucosal and systemic immunity. Here we produced oil-in-water nanoemulsion (NE) formulations containing various cationic and nonionic surfactants for use as adjuvants for the intranasal delivery of...

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Détails bibliographiques
Auteurs principaux: Wong, Pamela T., Wang, Su He, Ciotti, Susan, Makidon, Paul E., Smith, Douglas M., Fan, Yongyi, Schuler, Charles F., Baker, James R.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031264/
https://ncbi.nlm.nih.gov/pubmed/24320221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4005029
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