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Virus and Autoantigen-Specific CD4+ T Cells Are Key Effectors in a SCID Mouse Model of EBV-Associated Post-Transplant Lymphoproliferative Disorders

Polyclonal Epstein-Barr virus (EBV)-infected B cell line (lymphoblastoid cell lines; LCL)-stimulated T-cell preparations have been successfully used to treat EBV-positive post-transplant lymphoproliferative disorders (PTLD) in transplant recipients, but function and specificity of the CD4+ component...

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Bibliografische gegevens
Hoofdauteurs: Linnerbauer, Stefanie, Behrends, Uta, Adhikary, Dinesh, Witter, Klaus, Bornkamm, Georg W., Mautner, Josef
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031221/
https://ncbi.nlm.nih.gov/pubmed/24853673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004068
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