Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development.
Bone morphogenetic protein 4 (BMP-4) induces ventral mesoderm but represses dorsal mesoderm formation in Xenopus embryos. We show that BMP-4 inhibits two signaling pathways regulating dorsal mesoderm formation, the induction of dorsal mesoderm (Spemann organizer) and the dorsalization of ventral mes...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8618860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.26.12141 |
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