PARP-1 Val762Ala Polymorphism and Risk of Cancer: A Meta-Analysis Based on 39 Case-Control Studies

BACKGROUND: Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear chromatin-associated enzyme involved in several important cellular processes, particularly in the DNA repair system. PARP-1 rs1136410: C>T is among the most studied polymorphisms and likely involved in human carcinogenesis. However,...

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Главные авторы: Qin, Qin, Lu, Jing, Zhu, Hongcheng, Xu, Liping, Cheng, Hongyan, Zhan, Liangliang, Yang, Xi, Zhang, Chi, Sun, Xinchen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031170/
https://ncbi.nlm.nih.gov/pubmed/24853559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098022
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