Synthesis and Evaluation of a Molecularly Imprinted Polymer for Selective Solid-Phase Extraction of Irinotecan from Human Serum Samples

A molecularly imprinted polymer (MIP) was synthesized by non-covalent imprinting polymerization using irinotecan as template. Methacrylic acid and 4-vinylpyridine were selected as functional monomers. An optimized procedure coupled to LC-PDA analysis was developed for the selective solid-phase extra...

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Autores principales: Roy, Béatrice, Duy, Sung Vo, Puy, Jean-Yves, Martin, Charlotte, Guitton, Jérome, Dumontet, Charles, Périgaud, Christian, Lefebvre-Tournier, Isabelle
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031021/
https://ncbi.nlm.nih.gov/pubmed/24956520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jfb3010131
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