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Hydration-Induced Phase Separation in Amphiphilic Polymer Matrices and its Influence on Voclosporin Release

Voclosporin is a highly potent, new cyclosporine-A derivative that is currently in Phase 3 clinical trials in the USA as a potential treatment for inflammatory diseases of the eye. Voclosporin represents a number of very sparingly soluble drugs that are difficult to administer. We therefore selected...

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Detalhes bibliográficos
Main Authors: Khan, I. John, Murthy, N. Sanjeeva, Kohn, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030927/
https://ncbi.nlm.nih.gov/pubmed/24955746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jfb3040745
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