Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice

Osteogenesis imperfecta (OI), or brittle bone disease, is most often caused by dominant mutations in the collagen I genes COL1A1/COL1A2, whereas rarer recessive OI is often caused by mutations in genes encoding collagen I-interacting proteins. Recently, mutations in the gene for the proteinase bone...

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Main Authors: Muir, Alison M., Ren, Yinshi, Butz, Delana Hopkins, Davis, Nicholas A., Blank, Robert D., Birk, David E., Lee, Se-Jin, Rowe, David, Feng, Jian Q., Greenspan, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030766/
https://ncbi.nlm.nih.gov/pubmed/24419319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu013
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