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A rotation-translation invariant molecular descriptor of partial charges and its use in ligand-based virtual screening

BACKGROUND: Measures of similarity for chemical molecules have been developed since the dawn of chemoinformatics. Molecular similarity has been measured by a variety of methods including molecular descriptor based similarity, common molecular fragments, graph matching and 3D methods such as shape ma...

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Hlavní autoři: Berenger, Francois, Voet, Arnout, Lee, Xiao Yin, Zhang, Kam YJ
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030740/
https://ncbi.nlm.nih.gov/pubmed/24887178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-6-23
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