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Broad protection against influenza infection by vectored immunoprophylaxis in mice

Neutralizing antibodies that target epitopes conserved among many strains of influenza virus have been recently isolated from humans. Here we demonstrate that adeno-associated viruses (AAV) encoding two such broadly neutralizing antibodies are protective against diverse influenza strains. Serum from...

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Bibliografiske detaljer
Main Authors: Balazs, Alejandro B., Bloom, Jesse D., Hong, Christin M., Rao, Dinesh S., Baltimore, David
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030719/
https://ncbi.nlm.nih.gov/pubmed/23728362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2618
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