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Effects of Estrogen and Estrus Cycle on Pharmacokinetics, Absorption and Disposition of Genistein in Female Sprague-Dawley Rats

Genistein is an active soy isoflavone with anticancer activities but it is unknown why it has a higher oral bioavailability in female than in male rats. Our study determined the effects of estrus cycle on genistein’s oral bioavailability. Female rats with various levels of estrogen were orally admin...

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Main Authors: Kulkarni, Kaustubh H., Yang, Zhen, Tao, Niu, Hu, Ming
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030716/
https://ncbi.nlm.nih.gov/pubmed/22757747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf204755g
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