CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells

Genome wide association studies (GWAS) of ten different cancers have identified pleiotropic cancer predisposition loci across a region of chromosome 5p15.33 that includes the TERT and CLPTM1L genes. Of these, susceptibility alleles for pancreatic cancer have mapped to the CLPTM1L gene, thus promptin...

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Hauptverfasser: Jia, Jinping, Bosley, Allen D., Thompson, Abbey, Hoskins, Jason W., Cheuk, Adam, Collins, Irene, Parikh, Hemang, Xiao, Zhen, Ylaya, Kris, Dzyadyk, Marta, Cozen, Wendy, Hernandez, Brenda Y., Lynch, Charles F., Loncarek, Jadranka, Altekruse, Sean F., Zhang, Lizhi, Westlake, Christopher J., Factor, Valentina M., Thorgeirsson, Snorri, Bamlet, William R., Hewitt, Stephen M., Petersen, Gloria M., Andresson, Thorkell, Amundadottir, Laufey T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030677/
https://ncbi.nlm.nih.gov/pubmed/24648346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3176
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