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Inhibition of eIF5A results in aberrant uterine NK cell function and embryo loss in mice

PROBLEM: The role of eukaryotic initiation factor 5A (eIF5A) in feto-maternal immunotolerance is poorly understood. METHODS OF STUDY: The effects of N1-guanyl-1,7-diaminoheptane (GC7), an inhibitor of eIF5A, on the proportion and function of natural killer (NK) cell subsets were investigated using f...

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Detalhes bibliográficos
Main Authors: Qin, Xiaoli, Liu, Xiaorui, Shan, Bin, Shi, Lijuan, Sharma, Surendra, Wu, Ji, Lin, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030494/
https://ncbi.nlm.nih.gov/pubmed/24382123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12194
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