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Modeling activated states of GPCRs: the rhodopsin template

Activation of G Protein-Coupled Receptors (GPCRs) is an allosteric mechanism triggered by ligand binding and resulting in conformational changes transduced by the transmembrane domain. Models of the activated forms of GPCRs have become increasingly necessary for the development of a clear understand...

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Autors principals: Niv, Masha Y., Skrabanek, Lucy, Filizola, Marta, Weinstein, Harel
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030242/
https://ncbi.nlm.nih.gov/pubmed/17103019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-006-9061-3
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