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Metals and cholesterol: two sides of the same coin in Alzheimer’s disease pathology

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease. It begins years prior to the onset of clinical symptoms, such as memory loss and cognitive decline. Pathological hallmarks of AD include the accumulation of β-amyloid in plaques and hyperphosphorylated tau in neurofibrillary tan...

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Detalhes bibliográficos
Main Authors: Wong, Bruce X., Hung, Ya Hui, Bush, Ashley I., Duce, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030154/
https://ncbi.nlm.nih.gov/pubmed/24860500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00091
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