Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection

Genome-wide association studies (GWAS) may have reached their limit of detecting common type 2 diabetes (T2D)–associated genetic variation. We evaluated the performance of current polygenic T2D prediction. Using data from the Framingham Offspring (FOS) and the Coronary Artery Risk Development in You...

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Detalhes bibliográficos
Main Authors: Vassy, Jason L., Hivert, Marie-France, Porneala, Bianca, Dauriz, Marco, Florez, Jose C., Dupuis, Josée, Siscovick, David S., Fornage, Myriam, Rasmussen-Torvik, Laura J., Bouchard, Claude, Meigs, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030114/
https://ncbi.nlm.nih.gov/pubmed/24520119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1663
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