Increased Interaction With Insulin Receptor Substrate 1, a Novel Abnormality in Insulin Resistance and Type 2 Diabetes

Insulin receptor substrate 1 (IRS1) is a key mediator of insulin signal transduction. Perturbations involving IRS1 complexes may lead to the development of insulin resistance and type 2 diabetes (T2D). Surprisingly little is known about the proteins that interact with IRS1 in humans under health and...

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Detalhes bibliográficos
Main Authors: Caruso, Michael, Ma, Danjun, Msallaty, Zaher, Lewis, Monique, Seyoum, Berhane, Al-janabi, Wissam, Diamond, Michael, Abou-Samra, Abdul B., Højlund, Kurt, Tagett, Rebecca, Draghici, Sorin, Zhang, Xiangmin, Horowitz, Jeffrey F., Yi, Zhengping
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030113/
https://ncbi.nlm.nih.gov/pubmed/24584551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1872
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