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Maternal Obesity Reduces Milk Lipid Production in Lactating Mice by Inhibiting Acetyl-CoA Carboxylase and Impairing Fatty Acid Synthesis

Maternal metabolic and nutrient trafficking adaptations to lactation differ among lean and obese mice fed a high fat (HF) diet. Obesity is thought to impair milk lipid production, in part, by decreasing trafficking of dietary and de novo synthesized lipids to the mammary gland. Here, we report that...

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Main Authors: Saben, Jessica L., Bales, Elise S., Jackman, Matthew R., Orlicky, David, MacLean, Paul S., McManaman, James L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029960/
https://ncbi.nlm.nih.gov/pubmed/24849657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098066
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