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β-catenin transcriptional activity is minimal in canine osteosarcoma and its targeted inhibition results in minimal changes to cell line behavior

Canine osteosarcoma (OS) is an aggressive malignancy associated with poor outcomes. Therapeutic improvements are likely to develop from an improved understanding of signaling pathways contributing to osteosarcoma development and progression. The Wnt signaling pathway is of interest for its role in o...

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Bibliografske podrobnosti
Main Authors: Piskun, Caroline M., Stein, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029915/
https://ncbi.nlm.nih.gov/pubmed/24256430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12077
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