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Subclinical Carbon Monoxide Limits Apoptosis in the Developing Brain After Isoflurane Exposure

BACKGROUND: Volatile anesthetics cause widespread apoptosis in the developing brain. Carbon monoxide (CO) has antiapoptotic properties, and exhaled endogenous CO is commonly rebreathed during low-flow anesthesia in infants and children, resulting in subclinical CO exposure. Thus, we aimed to determi...

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Bibliographic Details
Main Authors: Cheng, Ying, Levy, Richard J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029883/
https://ncbi.nlm.nih.gov/pubmed/24413549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000000030
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