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Rac1-Dependent Lamellipodial Motility in Prostate Cancer PC-3 Cells Revealed by Optogenetic Control of Rac1 Activity

The lamellipodium, an essential structure for cell migration, plays an important role in the invasion and metastasis of cancer cells. Although Rac1 recognized as a key player in the formation of lamellipodia, the molecular mechanisms underlying lamellipodial motility are not fully understood. Optoge...

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Hlavní autoři: Kato, Takuma, Kawai, Katsuhisa, Egami, Youhei, Kakehi, Yoshiyuki, Araki, Nobukazu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029798/
https://ncbi.nlm.nih.gov/pubmed/24848679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097749
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