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Inferring protein domains associated with drug side effects based on drug-target interaction network

BACKGROUND: Most phenotypic effects of drugs are involved in the interactions between drugs and their target proteins, however, our knowledge about the molecular mechanism of the drug-target interactions is very limited. One of challenging issues in recent pharmaceutical science is to identify the u...

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Detalhes bibliográficos
Main Authors: Iwata, Hiroaki, Mizutani, Sayaka, Tabei, Yasuo, Kotera, Masaaki, Goto, Susumu, Yamanishi, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029543/
https://ncbi.nlm.nih.gov/pubmed/24565527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-S6-S18
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