A Visualizable Chain-Terminating Inhibitor of Glycosaminoglycan Biosynthesis in Developing Zebrafish

Heparan sulfate (HS) and chondroitin sulfate (CS) glycosaminoglycans (GAG) are proteoglycan-associated polysaccharides with essential functions in animals. They have been studied extensively by genetic manipulation of biosynthetic enzymes, but chemical tools for probing GAG function are limited. HS...

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Detalhes bibliográficos
Main Authors: Beahm, Brendan J., Dehnert, Karen W., Derr, Nicolas L., Kuhn, Joachim, Eberhart, Johann K., Spillmann, Dorothe, Amacher, Sharon L., Bertozzi, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029504/
https://ncbi.nlm.nih.gov/pubmed/24554559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310569
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