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Administration of a nondepleting anti-CD25 monoclonal antibody reduces disease severity in mice infected with Trypanosoma cruzi

The role of CD25+ regulatory T cells during the course of Trypanosoma cruzi infection has been previously analyzed, and the bulk of results have shown a limited role for this T cell subpopulation. In this study, we have used an IgM, nondepleting monoclonal antibody (mAb) aiming at blocking interleuk...

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Bibliografski detalji
Glavni autori: Nihei, J., Cardillo, F., dos Santos, W. L. C., Pontes-de-Carvalho, L., Mengel, J.
Format: Artigo
Jezik:Inglês
Izdano: Akadémiai Kiadó 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029292/
https://ncbi.nlm.nih.gov/pubmed/24883199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/EuJMI.4.2014.2.6
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