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Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data

BACKGROUND: Chromatin immunoprecipitation (ChIP) experiments are now the most comprehensive experimental approaches for mapping the binding of transcription factors (TFs) to their target genes. However, ChIP data alone is insufficient for identifying functional binding target genes of TFs for two re...

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Detalhes bibliográficos
Main Authors: Yang, Tzu-Hsien, Wu, Wei-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029220/
https://ncbi.nlm.nih.gov/pubmed/24565265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-S6-S13
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