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Induction of lethal bystander effects in human breast cancer cell cultures by DNA-incorporated Iodine-125 depends on phenotype

PURPOSE: This study uses a three-dimensional cell culture model to investigate lethal bystander effects in human breast cancer cell cultures (MCF-7, MDA-MB-231) treated with (125)I-labeled 5-iodo-2′-deoxyuridine ((125)IdU). These breast cancer cell lines respectively form metastatic xenografts in nu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Akudugu, John M., Azzam, Edouard I., Howell, Roger W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029165/
https://ncbi.nlm.nih.gov/pubmed/22489958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2012.683511
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