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Two different network topologies yield bistability in models of mesoderm and anterior mesendoderm specification in amphibians

Understanding the Gene Regulatory Networks (GRNs) that underlie development is a major question for systems biology. The establishment of the germ layers is amongst the earliest events of development and has been characterised in numerous model systems. The establishment of the mesoderm is best char...

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Main Authors: Brown, L.E., King, J.R., Loose, M.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029075/
https://ncbi.nlm.nih.gov/pubmed/24650939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.03.015
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