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Azithromycin May Antagonize Inhaled Tobramycin When Targeting Pseudomonas aeruginosa in Cystic Fibrosis

Rationale: Recent studies of inhaled tobramycin in subjects with cystic fibrosis (CF) find less clinical improvement than previously observed. Nonhuman data suggest that in some strains of Pseudomonas aeruginosa, azithromycin can antagonize tobramycin. Objectives: We tested the hypothesis that conco...

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Detalhes bibliográficos
Main Authors: Nick, Jerry A., Moskowitz, Samuel M., Chmiel, James F., Forssén, Anna V., Kim, Sun Ho, Saavedra, Milene T., Saiman, Lisa, Taylor-Cousar, Jennifer L., Nichols, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028742/
https://ncbi.nlm.nih.gov/pubmed/24476418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201310-352OC
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