Azithromycin May Antagonize Inhaled Tobramycin When Targeting Pseudomonas aeruginosa in Cystic Fibrosis

Rationale: Recent studies of inhaled tobramycin in subjects with cystic fibrosis (CF) find less clinical improvement than previously observed. Nonhuman data suggest that in some strains of Pseudomonas aeruginosa, azithromycin can antagonize tobramycin. Objectives: We tested the hypothesis that conco...

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Bibliografske podrobnosti
Main Authors: Nick, Jerry A., Moskowitz, Samuel M., Chmiel, James F., Forssén, Anna V., Kim, Sun Ho, Saavedra, Milene T., Saiman, Lisa, Taylor-Cousar, Jennifer L., Nichols, David P.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028742/
https://ncbi.nlm.nih.gov/pubmed/24476418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201310-352OC
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