Azithromycin May Antagonize Inhaled Tobramycin When Targeting Pseudomonas aeruginosa in Cystic Fibrosis

Rationale: Recent studies of inhaled tobramycin in subjects with cystic fibrosis (CF) find less clinical improvement than previously observed. Nonhuman data suggest that in some strains of Pseudomonas aeruginosa, azithromycin can antagonize tobramycin. Objectives: We tested the hypothesis that conco...

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Autors principals: Nick, Jerry A., Moskowitz, Samuel M., Chmiel, James F., Forssén, Anna V., Kim, Sun Ho, Saavedra, Milene T., Saiman, Lisa, Taylor-Cousar, Jennifer L., Nichols, David P.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028742/
https://ncbi.nlm.nih.gov/pubmed/24476418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201310-352OC
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